Disease outbreaks, whether in animals or humans, do not occur every day. However, when they do, their impact can be devastating. AIDS, Ebola, bird flu (caused by highly pathogenic H5N1 avian influenza virus), and pandemic swine flu outbreaks (caused by variant H3N2 swine influenza virus) are just a few examples of highly infectious diseases that can spread quickly and wreak havoc on human and animal populations if not detected promptly and if effective prevention and control measures are not implemented immediately. This course will enable students to apply what they have learned about disease outbreaks towards the design and implementation of more effective biosafety and bio-containment protocols as well as practical but science-based disease prevention and control programs. The central question of this course addresses why and how deadly and catastrophic disease outbreaks continue to occur in animal and human populations despite scientific and technological advances. This “big question” will allow students, who are themselves members of society and are individuals with various backgrounds, to explore, analyze, investigate, discuss, and critique various types of information and how to use this information to gain a better understanding of how disease outbreaks occur and develop new or improved methods to prevent and control these outbreaks.